Friday, December 24, 2010

DHT AND PROSTATE CANCER BY JERRY BRAINUM

Dihydrotestosterone or DHT is a metabolite of testosterone. The body produces DHT from testosterone by the actions of the enzyme, 5-alpha reductase. In most tissues of the body, DHT is the predominant androgen, since it binds to the androgen cell receptor 5-times greater than does testosterone. In muscle, however, DHT is rapidly degraded by enzymes, making testosterone the predominant androgen in muscle tissue. DHT, among other effects, plays a major role in the development of male sex organs. On the negative side, DHT is associated with male pattern baldness, acne onset, and prostate gland enlargement.
    In the prostate gland, DHT is the major androgen, not testosterone. Many studies have suggested that DHT stimulation of prostatic glandular tissue may be a root cause of prostate cancer. Most doctors are averse to providing supplemental testosterone treatment, even to men with a clear clinical deficiency of the hormone, because of fears of initiating prostate cancer onset. This fear is unfounded, since the prostate is receptive to normal blood levels of testosterone, and taking anything above this amount doesn't have any effect on the prostate. Conversely, having a chronic low testosterone level can induce subtle changes in the gland that may result in prostate cancer.
    Some doctors think that even if testosterone itself won't adversely affect the prostate gland, the fact that testosterone is converted into DHT by way of 5-alpha reductase makes testosterone therapy a hazardous choice. They are assuming that using any type of testosterone drug will lead to higher levels of DHT, and thereby increase the chances of prostate cancer. This notion was examined in a new study that involved 31 healthy men, ages 35 to 55. These men received either a DHT gel preparation or a placebo for one month. After four weeks, 27 men completed the study. In those who used the DHT gel, blood levels of DHT rose sevenfold, while testosterone levels decreased, presumably due to a negative feedback effect to the brain. In the placebo group, testosterone (T) levels remained unchanged. But the levels of DHT inside the prostate gland didn't differ between those who used the DHT drug and those who did not. In addition, other measures of prostate growth and function, including PSA, epithelial cell proliferation (an indicator of cancer), and androgen-related gene expression were not different between groups.
     Thus, this study shows that DHT activity mimics that of supplemental testosterone, in that although blood levels may increase when you use these hormones, the levels inside of the prostate gland don't change. This is further proof of the notion that testosterone causes prostate cancer is rubbish.

Page, S, et al. Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: A randomized-controlled trial. J Clin Endocrin Metabol 2010: in press.

©,2015 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited

Have you been ripped off  by supplement makers whose products don’t work as advertised? Want to know the truth about them? Check out Jerry Brainum's book Natural Anabolics, available at JerryBrainum.com.

 

The Applied Ergogenics blog is a collection of articles written and published by Jerry Brainum over the past 20 years. These articles have appeared in Muscle and Fitness, Ironman, and other magazines. Many of the posts on the blog are original articles, having appeared here for the first time. For Jerry’s most recent articles, which are far more in depth than anything that appears on this blog site, please subscribe to his Applied Metabolics Newsletter, at www.appliedmetabolics.com. This newsletter, which is more correctly referred to as a monthly e-book, since its average length is 35 to 40 pages, contains the latest findings about nutrition, exercise science, fat-loss, anti-aging, ergogenic aids, food supplements, and other topics. For 33 cents a day you get the benefit of Jerry’s 53 years of writing and intense study of all matters pertaining to fitness,health, bodybuilding, and disease prevention.

 

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Thursday, December 23, 2010

Will the real Vitamin D please stand up? by Jerry Brainum

To say that Vitamin D is an ascending star in the nutrition world is putting it mildly. D when from being a nutrient known only as a co-factor in calcium uptake into the body to a nutrient whose bounds seem to not end. Much of this resulted from the discovery of vitamin D receptors in various organs and tissues throughout the body. This shouldn't have been too surprising, considering that D is actually just a prohormone. In the body, D is converted in the liver and kidneys into an active hormone, known as a "secosteroid," that does a multitude of beneficial things in the body. The interaction of this activated form of D is linked to lower rates of just about every degenerative disease known to mankind, including cardiovascular disease and cancer.One reason for this universal health protective property of D is that it's required for the complete activation of T-cells, immune cells that among other functions, protect against viruses and tumor development in the body. Activated or hormonal D has also been shown to help prevent type-2 diabetes, a disease that is alarmingly on the rise worldwide.
      D is unique among nutrients in that it can be obtained simply through exposure to a certain spectrum of ultra violet light, as is produced from sun exposure. What happens here is that cholesterol in the skin is enzymatically converted into D. It takes about 15 minutes of UV exposure to produce about 10,000 units of D in the body. But some people are concerned about even this small level of sun exposure, mainly because of admonitions from doctors about the risks of acquiring skin cancer. The other problem with this is that during the Winter, some places just don't get enough sun exposure, so you would then have to depend on food sources. Good luck with that, since good natural food sources of D are far and few between. The obvious solution to this problem is to ingest vitamin D supplements.
       Recently, an "expert" science panel concluded that vitamin D supplements are superfluous, and probably dangerous, since most people show normal levels of activated D in their blood. But what these scientists considered  an optimal blood level of D differed from that offered by other scientists more versed in vitamin D research. According to the latter group, most people are likley deficient in the optimal blood levels of activated D, and should take a D supplement.
     That's the next controversy about D: which type of D is best? D comes in two forms, D3 and D2, with the latter being synthetic, produced as a result of irradiating sheep wool. For years, experts always advised people to stick to the natural (D3) form, noting that it's retained longer in the body compared to the synthetic D2 version. But others noted that the biological activity of D2 had been adjusted in terms of units per dose to match that of the natural form of D, or D3. One study even directly compared the two forms of D, with the conclusion being that they were biologically equal.
      In a new study, however, which again compared the two forms of D head to head, D3 again proved superior. This study involved 33 healthy adults, who were given D at a dose of 50,000 units a week for 12 weeks. The results showed that natural D3 was about 87% more potent  compared to D2 in raising activated D levels in the blood, and also showed 2-3 times greater storage in the body than the same dose of D2. As such, D3 is the best form of D supplement to use. This however, is a moot point, since I've never seen a stand-alone D2 supplement, although it's often the form used in vitamin-mineral supplements, and in milk. As for the dose, most experts suggest that 2,000 units a day is a good start. But to be precise, it would be better to take a baseline blood test for the activated D form. Good levels start at 30 or higher, with about 50 being optimal. Those who are old, fat, or have darker skin, may need to ingest higher levels of D to reach the optimal level.

Heaney, RP, et al, Vitamin D3 is more potent than Vitamin D2 in humans.J Clin Endocrin Metab 2010: in press.
  

©,2015 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited

Have you been ripped off  by supplement makers whose products don’t work as advertised? Want to know the truth about them? Check out Jerry Brainum's book Natural Anabolics, available at JerryBrainum.com.

 

The Applied Ergogenics blog is a collection of articles written and published by Jerry Brainum over the past 20 years. These articles have appeared in Muscle and Fitness, Ironman, and other magazines. Many of the posts on the blog are original articles, having appeared here for the first time. For Jerry’s most recent articles, which are far more in depth than anything that appears on this blog site, please subscribe to his Applied Metabolics Newsletter, at www.appliedmetabolics.com. This newsletter, which is more correctly referred to as a monthly e-book, since its average length is 35 to 40 pages, contains the latest findings about nutrition, exercise science, fat-loss, anti-aging, ergogenic aids, food supplements, and other topics. For 33 cents a day you get the benefit of Jerry’s 53 years of writing and intense study of all matters pertaining to fitness,health, bodybuilding, and disease prevention.

 

See Jerry's book at  http://www.jerrybrainum.com

 

Want more evidence-based information on exercise science, nutrition and food supplements, ergogenic aids, and anti-aging research? Check out Applied Metabolics Newsletter at www.appliedmetabolics.com

 

Wednesday, December 22, 2010

GAKIC outed! by Jerry Brainum

Since the ratio of production costs and retail prices are very high in the supplement industry, there is a constant search for new and allegedly "revolutionary" substances to include in products that are targeted for bodybuilders, athletes, and fitness enthusiasts. Creatine, for example, was introduced to the commercial market in 1993, although it had been used by Russian and East German athletes for over 30 previous years. Creatine, which is synthesized in the body from three amino acids in the liver, kidney, and pancreas, has shown itself over the years to be perhaps the most reliable sports supplement available. Study after study continues to prove the efficacy of creatine supplementation for 80 percent of those who ingest it. The 20% that fail to show any benefits from creatine usage are usually extensive meat eaters. Meat is the highest natural source of creatine.
    Based on the success of creatine, other substances have been introduced to the commercial market in the hopes of becoming the "new creatine." One such supplement was HMB, a metabolite of the amino acid, leucine. Initial studies of HMB, almost exclusively published by University of Iowa scientists who had discovered and applied for a use patent on HMB, found that HMB appeared to offer anti-catabolic effects in muscle that resulted in increased muscle strength and recovery. These studies,however, all involved untrained college students. When later studies were done using more experienced subjects, HMB flopped miserably. It didn't work any better than a placebo in increasing muscle strength and recovery. Since then, HMB has been shown to be useful for those new to weight-training and for older people. But initial ads for HMB declared that it"worked like Deca!" a reference to Deca-Durabolin, an injectable anabolic steroid.
      About a decade ago, University of Florida scientists developed an amino acid-based product that was again hailed as the next great bodybuilding supplement. This supplement consisted of glycine, an amino acid;arginine, another amino acid, and alpha-ketoisocaproic acid, which is a step above HMB in the metabolism of the essential amino  acid, leucine. The new substance went by the acronym 'GAKIC." Two studies examined the ergogenic effects of GAKIC during high intensity exercise, with one study involving maximal isokinetic leg extensions, and the other five repeated wind sprints of 10 seconds each on a stationary cycle. The study that focused on leg extensions found a 28% increase in muscle force production, with a 12% increase in total muscle work capacity when compared to a placebo. The stationary cycling study likewise also showed a significant increase in power output in subjects who ingested GAKIC compared to those who ingested a placebo. The two studies had one thing in common besides testing the effect of GAKIC: All the subjects in both studies were untrained college students. In this sense, the findings were similar to those of early HMB studies.
      As to how GAKIC produced its ergogenic effect, the prevailing theory was that the components of GAKIC had the ability to rapidly detoxify the accumulation of ammonia in working muscles. Ammonia is produced during intense exercise by the breakdown of purine nucleotides, such as those contained in ATP, as well as the breakdown of amino acids. A large increase of ammonia in working muscle is associated with fatigue onset. So it makes sense that reducing ammonia increases during intense exercise should make muscles more efficient.
    But a new study again tested GAKIC, but this time the study used 10 trained, experienced cyclists. The cyclists ingested 11.2 grams of GAKIC  or a placebo in a controlled, double-blind and randomized manner, 45 minutes before engaging in 10 sprints of 10 seconds each, separated by 50 second rest intervals on a stationary bike. This design was almost identical to one of the two initial GAKIC studies that showed an ergogenic effect.The updated results showed no differences in mean or peak power, or fatigue between those who ingested GAKIC compared to those who ingested a placebo.As such, this study duplicated the previous findings about HMB: it may work in those with no training experience, but fails to do anything at all in more experienced trainees.
      And similarly to HMB, GAKIC is not cheap. The list price for a product called  "GAKIC Hardcore" sold by Iovate or MuscleTech is $79.99, but the typical online price is $51.95, still rather expensive for a product that doesn't work for anyone with training experience. MuscleTech quickly secured the exclusive right to sell GAKIC from the University of Florida scientists who developed it and held the use patent soon after the initial two studies were published about GAKIC. I was sent the product right after it became available. The first thing I noticed was that it seemed to work for only about four days, then nothing. I tried it again, twice more with a week separation between usage, and the same thing happened. I now believe  that my first impression of efficacy for four days was, in fact, a placebo effect. I believed it would decrease fatigue during my training, and it did--for four days.
     If there is a lesson to be learned about GAKIC it's this: don't be swayed by the publication of only two studies into buying any product. Also be aware that what works for untrained college students, or anyone else who is not experienced, may not produce the same results in those with more training experience. And for Heaven's sake, although GAKIC at least featured human subjects, don't fall prey to buying an expensive supplement that has only either in vitro (isolated cell studies) or animal studies to "prove" its efficacy. These don't mean a thing in relation to human usage, and more often than not, often don't pan out when tested in intact human bodies.
 
Beis L, et al Failure of glycine-arginine-a-ketoisocaproic acid to improve high intensity exercise performance in trained cyclists.Int J Sports Nut Exercise Metabol 2010: in press.


©,2013 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited

Have you been ripped off  by supplement makers whose products don’t work as advertised? Want to know the truth about them? Check out Jerry Brainum's book Natural Anabolics, available at JerryBrainum.com.

 

The Applied Ergogenics blog is a collection of articles written and published by Jerry Brainum over the past 20 years. These articles have appeared in Muscle and Fitness, Ironman, and other magazines. Many of the posts on the blog are original articles, having appeared here for the first time. For Jerry’s most recent articles, which are far more in depth than anything that appears on this blog site, please subscribe to his Applied Metabolics Newsletter, at www.appliedmetabolics.com. This newsletter, which is more correctly referred to as a monthly e-book, since its average length is 35 to 40 pages, contains the latest findings about nutrition, exercise science, fat-loss, anti-aging, ergogenic aids, food supplements, and other topics. For 33 cents a day you get the benefit of Jerry’s 53 years of writing and intense study of all matters pertaining to fitness,health, bodybuilding, and disease prevention.

 

See Jerry's book at  http://www.jerrybrainum.com

 

Want more evidence-based information on exercise science, nutrition and food supplements, ergogenic aids, and anti-aging research? Check out Applied Metabolics Newsletter at www.appliedmetabolics.com

 

Monday, December 20, 2010

New Omega-3 fatty acid studies by Jerry Brainum

Omega-3 fatty acids are well-known for their health protective effects, particularly in regard to cardiovascular protection. Some studies also suggest that ingestion of omega-3 fatty acids may help increase bodyfat oxidation or "fat-burning." The omega-3 fatty acids consist of three fatty acids: alpha linoleic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). ALA is a precursor for the two active forms of omega-3, EPA and DHA. But the body can only convert small amounts, about 3-5% of ALA into EPA,with the conversion of ALA into DHA being almost negligible in men, although higher in women.Clearly, if you want to obtain the full benefit of omega-3 fatty acids, you need to either eat fatty fish, such as haddock, mackerel,sardines, anchovies, and others, or use omega-3 fish oil supplements. What isn't established yet is the optimal doses of pre-formed omega-3 fats to ingest, although the usual recommendation is to ingest about 1 gram a day of EPA and DHA.
     One little-known way to maximize levels of EPA and DHA in the blood is to eat foods rich in flavonoids. Flavonoids are found mostly in fruits and vegetables. In a recent rat study reported in the Journal of Nutrition, Rats were provided with either anthocyanin, a flavonoid from corn and other sources, or a diet without the flavonoid. The results of the study, which was replicated two more times, shows that ingesting flavonoids boosts blood levels of EPA and DHA significantly.
    Another study tested the effects of omega-3 fats on muscle protein synthesis in older people. Older people tend to lose muscle faster, a condition called sarcopenia, and some scientists suggest that it could be the result of both lack of exercise and a blunted protein synthesis effect in muscle. In the new study, to be published in the American Journal of Clinical Nutrition,16 healthy older adults were randomly assigned to receive either omega-3 fatty acids or corn oil for 8 weeks. Corn oil is largely composed of omega-6 fatty acids. The study authors monitored  the rate of muscle protein synthesis, and also the effect on key elements in the muscle protein synthesis pathway. These were evalulated both on an empty stomach, and during conditions of high blood amino acid and insulin levels. The latter is associated with increased muscle protein synthesis. The results showed no effect of corn oil, nor any effect of omega-3 without the presence of food. But under conditions of high insulin and amino acids, the omega-3 significantly boosted muscle protein synthesis in the subjects, as well as anabolic signaling factors. While this study involved older people who tend to have blunted muscle protein synthesis reactions, the implication of the study are that ingesting omega-3 fats may also provide a synergistic effect with amino acids for boosting muscle protein synthesis in younger people. In that respect, fish oil supplements can be viewed as "anabolic."
     Another study, also in the American Journal of Clinical Nutrition, compared higher doses and the suggested dose of one gram of DHA and EPA on markers of inflammation and high triglyceride (fat) levels in the blood. The high dose of EPA and DHA was 3.4 grams a day compared to 0.86 grams a day in the lower dose group. This was supplied to 23 men and 3 older women, all of whom showed high blood triglyceride levels. A placebo was also provided. The results showed that the higher dose of omega-3 lowered lowered triglycerides by 27% compared to the placebo, while the lower dose had no effect. But neither dose showed any effect on endothelial function (blood vessel reactions) or inflammation over 8 weeks. Those who advocate omega-3 fats to treat inflammation suggest considerably higher doses for this, averaging 10-15 grams daily.
     As noted earlier, fish oil is often suggested as an aid for fat loss, and some studies have shown some efficiency in this regard. In a new study from the American Journal of Clinical Nutrition, 128 overweight people were assigned to receive either 5 fish oil caps a day or  a placebo for 6 months. They also dieted and exercised. At the end of 6 months, no differences were observed in weight loss between those who ingested the fish oil or those who ingested a placebo. Once again, however, the dose of fish oil provided may not have been enough for this purpose.

 ©,2015 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited

Have you been ripped off  by supplement makers whose products don’t work as advertised? Want to know the truth about them? Check out Jerry Brainum's book Natural Anabolics, available at JerryBrainum.com

 

The Applied Ergogenics blog is a collection of articles written and published by Jerry Brainum over the past 20 years. These articles have appeared in Muscle and Fitness, Ironman, and other magazines. Many of the posts on the blog are original articles, having appeared here for the first time. For Jerry’s most recent articles, which are far more in depth than anything that appears on this blog site, please subscribe to his Applied Metabolics Newsletter, at www.appliedmetabolics.com. This newsletter, which is more correctly referred to as a monthly e-book, since its average length is 35 to 40 pages, contains the latest findings about nutrition, exercise science, fat-loss, anti-aging, ergogenic aids, food supplements, and other topics. For 33 cents a day you get the benefit of Jerry’s 53 years of writing and intense study of all matters pertaining to fitness,health, bodybuilding, and disease prevention.

 

See Jerry's book at  http://www.jerrybrainum.com

 

Want more evidence-based information on exercise science, nutrition and food supplements, ergogenic aids, and anti-aging research? Check out Applied Metabolics Newsletter at www.appliedmetabolics.com

 

Friday, December 17, 2010

An ironclad road to death? by Jerry Brainum

In recent years it has become apparent that many degenerative diseases have a large oxidative component. While the body does have innate protective antioxidant systems, represented by enzymes such as superoxide dismutase, catalase, and glutathione, these enzymes gradually become less active as we age. This opens the door to such maladies as cardiovascular disease, cancer, and brain degeneration represented by Alzheimer's, Parkinson's and others. But where does all this increased oxidation come from? Some scientists suggest that minerals that can act as oxidants, such as iron and copper are the key.
     One such scientist is Professor Douglas Kell, who recently wrote an exhaustive review in the journal Archives of Toxicology pointing an accusing finger at excess free iron. Normally iron is carried in the blood bound tightly to proteins, such as transferritin, and also hemoglobin in red blood cells. It's also stored with another protein called ferritin. The point here is that when iron is bound to these various proteins, it does not cause any damage in the body, unless you have a genetic disease such as hemochromotosis, in which large amounts of iron build up in the body.The problem is that iron has a tendency to become displaced from its protein-binders in blood and tissue. When that happens, the free or unbound iron becomes very reactive when exposed to oxygen. One product that results from this reaction is hydroxyl free radicals, which can damage cellular membranes through oxidation. The oxidation effect of iron is magnified when exposed to vitamin C, which combined with free--not bound--iron increases oxidation and cellular damage. This doesn't mean that vitamin C is dangerous;it's only a problem when it encounters free iron in the blood.
    You may have heard about resveratrol, a compound found in plants such as grapes, and also in red wine that is touted as offering many health benefits, including antiaging effects. It turns out that one of the main benefits of resveratrol is that it binds to or chelates free iron and copper, thus acting like the built-in iron-binding proteins of the body to prevent free iron-induced oxidative reactions. These reactions, by the way, are particularly damaging to the brain because the brain is loaded with polyunsaturated fat that is easily oxidized. You can protect yourself against such reactions by consuming natural supplements and foods that bind to free iron. Besides resveratrol, various berries, such as blueberries, as well as green tea contain polyphenols that will prevent iron oxidation in the body. Doing so may spare your brain and body from the ravages of aging.

 ©,2015 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited

Have you been ripped off  by supplement makers whose products don’t work as advertised? Want to know the truth about them? Check out Jerry Brainum's book Natural Anabolics, available at JerryBrainum.com.

 

The Applied Ergogenics blog is a collection of articles written and published by Jerry Brainum over the past 20 years. These articles have appeared in Muscle and Fitness, Ironman, and other magazines. Many of the posts on the blog are original articles, having appeared here for the first time. For Jerry’s most recent articles, which are far more in depth than anything that appears on this blog site, please subscribe to his Applied Metabolics Newsletter, at www.appliedmetabolics.com. This newsletter, which is more correctly referred to as a monthly e-book, since its average length is 35 to 40 pages, contains the latest findings about nutrition, exercise science, fat-loss, anti-aging, ergogenic aids, food supplements, and other topics. For 33 cents a day you get the benefit of Jerry’s 53 years of writing and intense study of all matters pertaining to fitness,health, bodybuilding, and disease prevention.

 

See Jerry's book at  http://www.jerrybrainum.com

 

Want more evidence-based information on exercise science, nutrition and food supplements, ergogenic aids, and anti-aging research? Check out Applied Metabolics Newsletter at www.appliedmetabolics.com

 

Monday, December 6, 2010

Myostatin: perhaps not so great after all by Jerry Brainum

Myostatin is a protein that was discovered in 1997 by researchers at Johns Hopkins University Medical School. The primary function of myostatin is to prevent muscle growth. In doing so, it works with other catabolic pathways in the body, including those involving the release of cortisol, the primary catabolic hormone. Animals deficient in myostatin show extreme muscle mass, along with decreased bodyfat. Naturally, such an outcome is very attractive to bodybuilders. This led to the premature release of a supplement derived from seaweed that was marketed as a "myostatin blocker." This particular property of the seaweed was produced in one in vitro study. This means that the substance blocked myostatin, but in a test-tube. There was no evidence that it duplicated this effect in an intact human body.
      The fact that there was no real evidence that the reputed myostain blocking supplement actually worked didn't deter greedy companies from touting the supplement. I had a feeling at the time that the supplement was useless, and wrote this in a bodybuilding magazine. Not long afterward, studies done with human subjects confirmed that the touted myostain blocking supplement did not work as advertised. Since that time, other alleged myostain-blocking supplements have appeared on the market. One is based on follistatin, another naturally occuring protein that does appear to block the effects of myostatin in the body. But follistatin, being a protein, is degraded in the gut before it can become active if consumed orally. The studies showing that follistatin blocked myostatin involved follistatin being injected into mice and rats. The producers of the follistatin supplement have yet to produce a human study showing that it works, although they have published anecdotal reports of efficacy, as well as an in house study, which is useless.
      While the properties of myostatin may appear to hold tremendous potential for those seeking added muscle mass, there are lesser known effects of blocking myostatin that may take the wind out of the sails of those dreaming about massive muscles with myostatin blocking. For one, there is evidence that while blocking myostatin will indeed increase muscle mass, it doesn't offer any boost in muscle strength. The latest study to report this effect compared mice bred to completely lack myostatin and normal mice. While the myostatin-deficient mice (or null mice) showed larger muscle size, they did not show any increased strength. Even worse, examination of muscle fibers of the myostatin null mice showed increased degeneration. Other studies show that myostatin plays a role in tendon regeneration, and blocking myostatin can result in an increased rate of tendon injuries. So my advice is to avoid all reputed myostatin blocking supplements, especially since none of them work. There are experiemental drugs that do effectively block myostatin, but taking such drugs now could be hazardous to health, since all the biological nuances of myostatin have yet to be established.

 
Gentry, B, et al. Hindlimb skeletal muscle function in myostatin-deficient mice. Muscle and Nerve 2010: in press.

  
©,2015 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited

Have you been ripped off  by supplement makers whose products don’t work as advertised? Want to know the truth about them? Check out Jerry Brainum's book Natural Anabolics, available at JerryBrainum.com.

 

The Applied Ergogenics blog is a collection of articles written and published by Jerry Brainum over the past 20 years. These articles have appeared in Muscle and Fitness, Ironman, and other magazines. Many of the posts on the blog are original articles, having appeared here for the first time. For Jerry’s most recent articles, which are far more in depth than anything that appears on this blog site, please subscribe to his Applied Metabolics Newsletter, at www.appliedmetabolics.com. This newsletter, which is more correctly referred to as a monthly e-book, since its average length is 35 to 40 pages, contains the latest findings about nutrition, exercise science, fat-loss, anti-aging, ergogenic aids, food supplements, and other topics. For 33 cents a day you get the benefit of Jerry’s 53 years of writing and intense study of all matters pertaining to fitness,health, bodybuilding, and disease prevention.

 

See Jerry's book at  http://www.jerrybrainum.com

 

Want more evidence-based information on exercise science, nutrition and food supplements, ergogenic aids, and anti-aging research? Check out Applied Metabolics Newsletter at www.appliedmetabolics.com