A study presented at the NSCA conference by researchers from the University of Connecticut examined whether taking short rests between sets influences the release of growth hormone during exercise. The subjects were 10 bodybuilders with at least four years of training experience and 10 untrained but physically active men. The bodybuilders had previously trained on programs that featured short rests between sets. For the study both groups did six sets of 10 reps on the squat, resting two minutes between sets.
Both the trained and untrained men showed similar resting GH levels, and both groups showed a significant rise in the hormone after the workout. The trained men, however, produced more lactic acid, which stimulates GH release during exercise. The ability to train at higher level of lactic acid release appears to enable more-experienced bodybuilders to produce a superior GH response to exercise.
Recently, several studies have appeared that downplay the role of an exercise-induced anabolic hormone increase. According to these studies, the transitory increases in levels of growth hormone and testosterone after intense exercise doesn't appear to play as important a role in promoting gains in muscular size and strength as was previously believed. These researchers instead say that what's really important is the intensity level of the exercise and the force of muscular contractions, both of which promote an upgrading of muscle protein synthesis. It's the upgraded muscle protein synthesis resulting from exercise, rather than the rise in anabolic hormones, that is the key player in promoting gains in muscular size and strength. Or so say these researchers. What is undeniable, however, is the role of autocrine or intramuscular release of anabolic hormones induced by exercise. These include two variants of insulinlike growth factor-1 (IGF-1), namely IFG-1Ea and mechano growth factor (MGF). These locally produced anabolic hormones are essential for the use of muscle satellite cells, which are a type of stem cell used for muscle repair and growth.In this sense, anabolic hormones, at least that produced within muscle, are important and vital for promoting muscle gains.
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